diff --git a/android/prebuilt.go b/android/prebuilt.go
index 13cda9d..5a94a0f 100644
--- a/android/prebuilt.go
+++ b/android/prebuilt.go
@@ -534,6 +534,35 @@
 		for _, moduleInFamily := range allModulesInFamily {
 			if moduleInFamily.Name() != selectedModuleInFamily.Name() {
 				moduleInFamily.HideFromMake()
+				// If this is a prebuilt module, unset properties.UsePrebuilt
+				// properties.UsePrebuilt might evaluate to true via soong config var fallback mechanism
+				// Set it to false explicitly so that the following mutator does not replace rdeps to this unselected prebuilt
+				if p := GetEmbeddedPrebuilt(moduleInFamily); p != nil {
+					p.properties.UsePrebuilt = false
+				}
+			}
+		}
+	}
+	// Do a validation pass to make sure that multiple prebuilts of a specific module are not selected.
+	// This might happen if the prebuilts share the same soong config var namespace.
+	// This should be an error, unless one of the prebuilts has been explicitly declared in apex_contributions
+	var selectedPrebuilt Module
+	for _, moduleInFamily := range allModulesInFamily {
+		// Skip if this module is in a different namespace
+		if !moduleInFamily.ExportedToMake() {
+			continue
+		}
+		// Skip for the top-level java_sdk_library_(_import). This has some special cases that need to be addressed first.
+		// This does not run into non-determinism because PrebuiltPostDepsMutator also has the special case
+		if sdkLibrary, ok := moduleInFamily.(interface{ SdkLibraryName() *string }); ok && sdkLibrary.SdkLibraryName() != nil {
+			continue
+		}
+		if p := GetEmbeddedPrebuilt(moduleInFamily); p != nil && p.properties.UsePrebuilt {
+			if selectedPrebuilt == nil {
+				selectedPrebuilt = moduleInFamily
+			} else {
+				ctx.ModuleErrorf("Multiple prebuilt modules %v and %v have been marked as preferred for this source module. "+
+					"Please add the appropriate prebuilt module to apex_contributions for this release config.", selectedPrebuilt.Name(), moduleInFamily.Name())
 			}
 		}
 	}
@@ -562,7 +591,7 @@
 						// If we do not special-case this here, rdeps referring to a java_sdk_library in next builds via libs
 						// will get prebuilt stubs
 						// TODO (b/308187268): Remove this after the apexes have been added to apex_contributions
-						if psi.IsSelected(*sdkLibrary.SdkLibraryName()) {
+						if psi.IsSelected(name) {
 							return false
 						}
 					}
@@ -625,6 +654,17 @@
 	CreatedByJavaSdkLibraryName() *string
 }
 
+// Returns true if the prebuilt variant is disabled
+// e.g. for a cc_prebuilt_library_shared, this will return
+// - true for the static variant of the module
+// - false for the shared variant of the module
+//
+// Even though this is a cc_prebuilt_library_shared, we create both the variants today
+// https://source.corp.google.com/h/googleplex-android/platform/build/soong/+/e08e32b45a18a77bc3c3e751f730539b1b374f1b:cc/library.go;l=2113-2116;drc=2c4a9779cd1921d0397a12b3d3521f4c9b30d747;bpv=1;bpt=0
+func (p *Prebuilt) variantIsDisabled(ctx BaseMutatorContext, prebuilt Module) bool {
+	return p.srcsSupplier != nil && len(p.srcsSupplier(ctx, prebuilt)) == 0
+}
+
 // usePrebuilt returns true if a prebuilt should be used instead of the source module.  The prebuilt
 // will be used if it is marked "prefer" or if the source module is disabled.
 func (p *Prebuilt) usePrebuilt(ctx BaseMutatorContext, source Module, prebuilt Module) bool {
@@ -639,7 +679,7 @@
 		return false
 	}
 	// If the prebuilt module is explicitly listed in the metadata module, use that
-	if isSelected(psi, prebuilt) {
+	if isSelected(psi, prebuilt) && !p.variantIsDisabled(ctx, prebuilt) {
 		return true
 	}
 
@@ -647,7 +687,7 @@
 	// fall back to the existing source vs prebuilt selection.
 	// TODO: Drop the fallback mechanisms
 
-	if p.srcsSupplier != nil && len(p.srcsSupplier(ctx, prebuilt)) == 0 {
+	if p.variantIsDisabled(ctx, prebuilt) {
 		return false
 	}
 
diff --git a/apex/apex_test.go b/apex/apex_test.go
index 74d6de8..9dc77c2 100644
--- a/apex/apex_test.go
+++ b/apex/apex_test.go
@@ -6199,7 +6199,7 @@
 		`)
 	})
 
-	t.Run("Co-existing unflagged apexes should create a duplicate deapexer error in hiddenapi processing", func(t *testing.T) {
+	t.Run("Co-existing unflagged apexes should create a duplicate module error", func(t *testing.T) {
 		bp := `
 		// Source
 		apex {
@@ -6273,7 +6273,7 @@
 		}
 	`
 
-		testDexpreoptWithApexes(t, bp, "Multiple installable prebuilt APEXes provide ambiguous deapexers: prebuilt_myapex.v1 and prebuilt_myapex.v2", preparer, fragment)
+		testDexpreoptWithApexes(t, bp, "Multiple prebuilt modules prebuilt_myapex.v1 and prebuilt_myapex.v2 have been marked as preferred for this source module", preparer, fragment)
 	})
 
 }
diff --git a/cc/prebuilt_test.go b/cc/prebuilt_test.go
index f6b5ed5..71b7e43 100644
--- a/cc/prebuilt_test.go
+++ b/cc/prebuilt_test.go
@@ -610,3 +610,153 @@
 		android.AssertStringEquals(t, "unexpected LOCAL_MODULE", "libbar", entries.EntryMap["LOCAL_MODULE"][0])
 	}
 }
+
+// Setting prefer on multiple prebuilts is an error, unless one of them is also listed in apex_contributions
+func TestMultiplePrebuiltsPreferredUsingLegacyFlags(t *testing.T) {
+	bp := `
+		// an rdep
+		cc_library {
+			name: "libfoo",
+			shared_libs: ["libbar"],
+		}
+
+		// multiple variations of dep
+		// source
+		cc_library {
+			name: "libbar",
+		}
+		// prebuilt "v1"
+		cc_prebuilt_library_shared {
+			name: "libbar",
+			srcs: ["libbar.so"],
+			prefer: true,
+		}
+		// prebuilt "v2"
+		cc_prebuilt_library_shared {
+			name: "libbar.v2",
+			stem: "libbar",
+			source_module_name: "libbar",
+			srcs: ["libbar.so"],
+			prefer: true,
+		}
+
+		// selectors
+		apex_contributions {
+			name: "myapex_contributions",
+			contents: [%v],
+		}
+		all_apex_contributions {name: "all_apex_contributions"}
+	`
+	hasDep := func(ctx *android.TestContext, m android.Module, wantDep android.Module) bool {
+		t.Helper()
+		var found bool
+		ctx.VisitDirectDeps(m, func(dep blueprint.Module) {
+			if dep == wantDep {
+				found = true
+			}
+		})
+		return found
+	}
+
+	testCases := []struct {
+		desc                   string
+		selectedDependencyName string
+		expectedDependencyName string
+		expectedErr            string
+	}{
+		{
+			desc:        "Multiple prebuilts have prefer: true",
+			expectedErr: "Multiple prebuilt modules prebuilt_libbar and prebuilt_libbar.v2 have been marked as preferred for this source module",
+		},
+		{
+			desc:                   "Multiple prebuilts have prefer: true. The prebuilt listed in apex_contributions wins.",
+			selectedDependencyName: `"prebuilt_libbar"`,
+			expectedDependencyName: "prebuilt_libbar",
+		},
+	}
+
+	for _, tc := range testCases {
+		preparer := android.GroupFixturePreparers(
+			android.FixtureRegisterWithContext(func(ctx android.RegistrationContext) {
+				android.RegisterApexContributionsBuildComponents(ctx)
+			}),
+			android.FixtureModifyProductVariables(func(variables android.FixtureProductVariables) {
+				variables.BuildFlags = map[string]string{
+					"RELEASE_APEX_CONTRIBUTIONS_ADSERVICES": "myapex_contributions",
+				}
+			}),
+		)
+		if tc.expectedErr != "" {
+			preparer = preparer.ExtendWithErrorHandler(android.FixtureExpectsAtLeastOneErrorMatchingPattern(tc.expectedErr))
+		}
+
+		ctx := testPrebuilt(t, fmt.Sprintf(bp, tc.selectedDependencyName), map[string][]byte{
+			"libbar.so": nil,
+			"crtx.o":    nil,
+		}, preparer)
+		if tc.expectedErr != "" {
+			return // the fixture will assert that the excepted err has been raised
+		}
+		libfoo := ctx.ModuleForTests("libfoo", "android_arm64_armv8-a_shared").Module()
+		expectedDependency := ctx.ModuleForTests(tc.expectedDependencyName, "android_arm64_armv8-a_shared").Module()
+		android.AssertBoolEquals(t, fmt.Sprintf("expected dependency from %s to %s\n", libfoo.Name(), tc.expectedDependencyName), true, hasDep(ctx, libfoo, expectedDependency))
+	}
+}
+
+// If module sdk cannot provide a cc module variant (e.g. static), then the module variant from source should be used
+func TestMissingVariantInModuleSdk(t *testing.T) {
+	bp := `
+		// an rdep
+		cc_library {
+			name: "libfoo",
+			static_libs: ["libbar"],
+		}
+
+		// source
+		cc_library {
+			name: "libbar",
+		}
+		// prebuilt
+		// libbar only exists as a shared library
+		cc_prebuilt_library_shared {
+			name: "libbar",
+			srcs: ["libbar.so"],
+		}
+		// selectors
+		apex_contributions {
+			name: "myapex_contributions",
+			contents: ["prebuilt_libbar"],
+		}
+		all_apex_contributions {name: "all_apex_contributions"}
+	`
+	hasDep := func(ctx *android.TestContext, m android.Module, wantDep android.Module) bool {
+		t.Helper()
+		var found bool
+		ctx.VisitDirectDeps(m, func(dep blueprint.Module) {
+			if dep == wantDep {
+				found = true
+			}
+		})
+		return found
+	}
+
+	preparer := android.GroupFixturePreparers(
+		android.FixtureRegisterWithContext(func(ctx android.RegistrationContext) {
+			android.RegisterApexContributionsBuildComponents(ctx)
+		}),
+		android.FixtureModifyProductVariables(func(variables android.FixtureProductVariables) {
+			variables.BuildFlags = map[string]string{
+				"RELEASE_APEX_CONTRIBUTIONS_ADSERVICES": "myapex_contributions",
+			}
+		}),
+	)
+	ctx := testPrebuilt(t, bp, map[string][]byte{
+		"libbar.so": nil,
+		"crtx.o":    nil,
+	}, preparer)
+	libfoo := ctx.ModuleForTests("libfoo", "android_arm64_armv8-a_shared").Module()
+	sourceLibBar := ctx.ModuleForTests("libbar", "android_arm64_armv8-a_static").Module()
+	// Even though the prebuilt is listed in apex_contributions, the prebuilt does not have a static variant.
+	// Therefore source of libbar should be used.
+	android.AssertBoolEquals(t, fmt.Sprintf("expected dependency from libfoo to source libbar"), true, hasDep(ctx, libfoo, sourceLibBar))
+}
diff --git a/java/androidmk.go b/java/androidmk.go
index b7df9bf..498962f 100644
--- a/java/androidmk.go
+++ b/java/androidmk.go
@@ -691,9 +691,10 @@
 		return nil
 	}
 	return []android.AndroidMkEntries{android.AndroidMkEntries{
-		Class:      "APPS",
-		OutputFile: android.OptionalPathForPath(a.outputFile),
-		Include:    "$(BUILD_SYSTEM)/soong_app_prebuilt.mk",
+		Class:        "APPS",
+		OutputFile:   android.OptionalPathForPath(a.outputFile),
+		OverrideName: a.BaseModuleName(), // TODO (spandandas): Add a test
+		Include:      "$(BUILD_SYSTEM)/soong_app_prebuilt.mk",
 		ExtraEntries: []android.AndroidMkExtraEntriesFunc{
 			func(ctx android.AndroidMkExtraEntriesContext, entries *android.AndroidMkEntries) {
 				entries.SetBoolIfTrue("LOCAL_PRIVILEGED_MODULE", a.Privileged())
diff --git a/java/dexpreopt.go b/java/dexpreopt.go
index 1cfa642..38ed856 100644
--- a/java/dexpreopt.go
+++ b/java/dexpreopt.go
@@ -187,6 +187,33 @@
 	return apexInfo.ForPrebuiltApex
 }
 
+// For apex variant of modules, this returns true on the source variant if the prebuilt apex
+// has been selected using apex_contributions.
+// The prebuilt apex will be responsible for generating the dexpreopt rules of the deapexed java lib.
+func disableSourceApexVariant(ctx android.BaseModuleContext) bool {
+	if !isApexVariant(ctx) {
+		return false // platform variant
+	}
+	apexInfo, _ := android.ModuleProvider(ctx, android.ApexInfoProvider)
+	psi := android.PrebuiltSelectionInfoMap{}
+	ctx.VisitDirectDepsWithTag(android.PrebuiltDepTag, func(am android.Module) {
+		psi, _ = android.OtherModuleProvider(ctx, am, android.PrebuiltSelectionInfoProvider)
+	})
+	// Find the apex variant for this module
+	_, apexVariantsWithoutTestApexes, _ := android.ListSetDifference(apexInfo.InApexVariants, apexInfo.TestApexes)
+	disableSource := false
+	// find the selected apexes
+	for _, apexVariant := range apexVariantsWithoutTestApexes {
+		for _, selected := range psi.GetSelectedModulesForApiDomain(apexVariant) {
+			// If the apex_contribution for this api domain contains a prebuilt apex, disable the source variant
+			if strings.HasPrefix(selected, "prebuilt_com.google.android") {
+				disableSource = true
+			}
+		}
+	}
+	return disableSource
+}
+
 // Returns whether dexpreopt is applicable to the module.
 // When it returns true, neither profile nor dexpreopt artifacts will be generated.
 func (d *dexpreopter) dexpreoptDisabled(ctx android.BaseModuleContext, libName string) bool {
@@ -216,6 +243,10 @@
 		return true
 	}
 
+	if disableSourceApexVariant(ctx) {
+		return true
+	}
+
 	if _, isApex := android.ModuleProvider(ctx, android.ApexBundleInfoProvider); isApex {
 		// dexpreopt rules for system server jars can be generated in the ModuleCtx of prebuilt apexes
 		return false