diff --git a/runtime/arch/instruction_set.cc b/runtime/arch/instruction_set.cc
index 8f64dcd..64af7ec 100644
--- a/runtime/arch/instruction_set.cc
+++ b/runtime/arch/instruction_set.cc
@@ -18,8 +18,8 @@
 
 // Explicitly include our own elf.h to avoid Linux and other dependencies.
 #include "../elf.h"
+#include "android-base/logging.h"
 #include "base/bit_utils.h"
-#include "base/logging.h"
 #include "globals.h"
 
 namespace art {
@@ -36,11 +36,9 @@
     case kNone:
       LOG(FATAL) << "Unsupported instruction set " << isa;
       UNREACHABLE();
-
-    default:
-      LOG(FATAL) << "Unknown ISA " << isa;
-      UNREACHABLE();
   }
+  LOG(FATAL) << "Unknown ISA " << isa;
+  UNREACHABLE();
 }
 
 const char* GetInstructionSetString(InstructionSet isa) {
@@ -60,10 +58,9 @@
       return "mips64";
     case kNone:
       return "none";
-    default:
-      LOG(FATAL) << "Unknown ISA " << isa;
-      UNREACHABLE();
   }
+  LOG(FATAL) << "Unknown ISA " << isa;
+  UNREACHABLE();
 }
 
 InstructionSet GetInstructionSetFromString(const char* isa_str) {
@@ -128,10 +125,9 @@
     case kNone:
       LOG(FATAL) << "ISA kNone does not have alignment.";
       UNREACHABLE();
-    default:
-      LOG(FATAL) << "Unknown ISA " << isa;
-      UNREACHABLE();
   }
+  LOG(FATAL) << "Unknown ISA " << isa;
+  UNREACHABLE();
 }
 
 #if !defined(ART_STACK_OVERFLOW_GAP_arm) || !defined(ART_STACK_OVERFLOW_GAP_arm64) || \
@@ -197,11 +193,9 @@
     case kNone:
       LOG(FATAL) << "kNone has no stack overflow size";
       UNREACHABLE();
-
-    default:
-      LOG(FATAL) << "Unknown instruction set" << isa;
-      UNREACHABLE();
   }
+  LOG(FATAL) << "Unknown instruction set" << isa;
+  UNREACHABLE();
 }
 
 }  // namespace art
diff --git a/runtime/arch/instruction_set.h b/runtime/arch/instruction_set.h
index 7ef9a7a..7203b18 100644
--- a/runtime/arch/instruction_set.h
+++ b/runtime/arch/instruction_set.h
@@ -93,7 +93,7 @@
 // Fatal logging out of line to keep the header clean of logging.h.
 NO_RETURN void InstructionSetAbort(InstructionSet isa);
 
-static inline PointerSize GetInstructionSetPointerSize(InstructionSet isa) {
+constexpr PointerSize GetInstructionSetPointerSize(InstructionSet isa) {
   switch (isa) {
     case kArm:
       // Fall-through.
@@ -109,23 +109,37 @@
       return kMipsPointerSize;
     case kMips64:
       return kMips64PointerSize;
-    default:
-      InstructionSetAbort(isa);
+
+    case kNone:
+      break;
   }
+  InstructionSetAbort(isa);
 }
 
-ALWAYS_INLINE static inline constexpr size_t GetInstructionSetInstructionAlignment(
-    InstructionSet isa) {
-  return (isa == kThumb2 || isa == kArm) ? kThumb2InstructionAlignment :
-         (isa == kArm64) ? kArm64InstructionAlignment :
-         (isa == kX86) ? kX86InstructionAlignment :
-         (isa == kX86_64) ? kX86_64InstructionAlignment :
-         (isa == kMips) ? kMipsInstructionAlignment :
-         (isa == kMips64) ? kMips64InstructionAlignment :
-         0;  // Invalid case, but constexpr doesn't support asserts.
+constexpr size_t GetInstructionSetInstructionAlignment(InstructionSet isa) {
+  switch (isa) {
+    case kArm:
+      // Fall-through.
+    case kThumb2:
+      return kThumb2InstructionAlignment;
+    case kArm64:
+      return kArm64InstructionAlignment;
+    case kX86:
+      return kX86InstructionAlignment;
+    case kX86_64:
+      return kX86_64InstructionAlignment;
+    case kMips:
+      return kMipsInstructionAlignment;
+    case kMips64:
+      return kMips64InstructionAlignment;
+
+    case kNone:
+      break;
+  }
+  InstructionSetAbort(isa);
 }
 
-static inline bool IsValidInstructionSet(InstructionSet isa) {
+constexpr bool IsValidInstructionSet(InstructionSet isa) {
   switch (isa) {
     case kArm:
     case kThumb2:
@@ -135,15 +149,16 @@
     case kMips:
     case kMips64:
       return true;
+
     case kNone:
-    default:
       return false;
   }
+  return false;
 }
 
 size_t GetInstructionSetAlignment(InstructionSet isa);
 
-static inline bool Is64BitInstructionSet(InstructionSet isa) {
+constexpr bool Is64BitInstructionSet(InstructionSet isa) {
   switch (isa) {
     case kArm:
     case kThumb2:
@@ -156,16 +171,17 @@
     case kMips64:
       return true;
 
-    default:
-      InstructionSetAbort(isa);
+    case kNone:
+      break;
   }
+  InstructionSetAbort(isa);
 }
 
-static inline PointerSize InstructionSetPointerSize(InstructionSet isa) {
+constexpr PointerSize InstructionSetPointerSize(InstructionSet isa) {
   return Is64BitInstructionSet(isa) ? PointerSize::k64 : PointerSize::k32;
 }
 
-static inline size_t GetBytesPerGprSpillLocation(InstructionSet isa) {
+constexpr size_t GetBytesPerGprSpillLocation(InstructionSet isa) {
   switch (isa) {
     case kArm:
       // Fall-through.
@@ -182,12 +198,13 @@
     case kMips64:
       return 8;
 
-    default:
-      InstructionSetAbort(isa);
+    case kNone:
+      break;
   }
+  InstructionSetAbort(isa);
 }
 
-static inline size_t GetBytesPerFprSpillLocation(InstructionSet isa) {
+constexpr size_t GetBytesPerFprSpillLocation(InstructionSet isa) {
   switch (isa) {
     case kArm:
       // Fall-through.
@@ -204,9 +221,10 @@
     case kMips64:
       return 8;
 
-    default:
-      InstructionSetAbort(isa);
+    case kNone:
+      break;
   }
+  InstructionSetAbort(isa);
 }
 
 size_t GetStackOverflowReservedBytes(InstructionSet isa);
@@ -243,7 +261,7 @@
 }
 
 // Use the lower 32b for the method pointer and the upper 32b for the code pointer.
-static inline TwoWordReturn GetTwoWordSuccessValue(uintptr_t hi, uintptr_t lo) {
+static inline constexpr TwoWordReturn GetTwoWordSuccessValue(uintptr_t hi, uintptr_t lo) {
   static_assert(sizeof(uint32_t) == sizeof(uintptr_t), "Unexpected size difference");
   uint32_t lo32 = lo;
   uint64_t hi64 = static_cast<uint64_t>(hi);
@@ -251,6 +269,10 @@
 }
 
 #elif defined(__x86_64__) || defined(__aarch64__) || (defined(__mips__) && defined(__LP64__))
+
+// Note: TwoWordReturn can't be constexpr for 64-bit targets. We'd need a constexpr constructor,
+//       which would violate C-linkage in the entrypoint functions.
+
 struct TwoWordReturn {
   uintptr_t lo;
   uintptr_t hi;